Otol Neurotol 21:513520 Qin X, Meghana K, Sowjanya NL, Sushma KR, Krishna CG, Manasa J, Jaya G, Sita A, Gowthami M, Honeyshmitha D, Srikanth G, Sreeharsha N (2019) Embelin attenuates cisplatin-induced nephrotoxicity: Involving inhibition of oxidative stress and inflammation in addition with activation of Nrf-2/HO-1 pathway
Abstract Plant glutathione S-transferases (GSTs) are ubiquitous and multifunctional enzymes encoded by large gene families
3.4.4 Alkaloids: comprehensive miRNA biogenesis modulation Berberine targets multiple oncogenic miRNAs, including miR-21 (5070% reduction in HCT116 cells), miR-23a (2.5-fold increase in hepatoma cells), and suppression of the miR-1792 cluster in multiple myeloma
Oxidative stress occurs when free radicals outnumber antioxidants, potentially leading to cellular damage